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  • RNA Therapeutics : The Evolving Landscape of RNA Therapeutics
    RNA Therapeutics : The Evolving Landscape of RNA Therapeutics

    RNA Therapeutics: The Evolving Landscape of RNA Therapeutics provides a comprehensive overview of RNA therapeutic modalities, from bench-to-bedside, with an emphasis on the increasingly impactful areas of gene therapy, oligonucleotide therapeutics, gene editing and delivery.International leaders in the field examine RNA-based therapeutics tools that have been developed to-date to modulate cellular processes such as transcription, translation and protein function.Approved RNA-based therapies and lessons learned from failed therapies are discussed in-depth, as are evolving advances in RNA biochemical analysis, and similar advances that are enabling clinical application of RNA-based therapies. Later sections discuss delivery technologies, remaining hurdles in research and translation, the therapy development process from the lab to the clinic, and novel RNA-based therapies currently in development.

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  • Applied RNA Bioscience
    Applied RNA Bioscience

    The focus of this book is to introduce up-to-date information on applications and practical use of RNA for agriculture, biotechnology and medicine.It provides unique ideas, tools, and methods in detail from a variety of scientific and technical disciplines. RNA science has progressed enormously in recent decades, and vast amounts of information on RNA functions and their regulatory mechanisms are becoming available.Such a progress opened the door to an age of practical application of RNA in many fields including agriculture, plant science, medical science, brewing and fermentation technology, and material production.This book inspires its readership and contributes to not only expansion in application of RNA but also to basic research.

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  • RNA Biology : An Introduction
    RNA Biology : An Introduction

    Written with biologists, biochemists and other molecular scientists in mind, this volume meets the long-felt need for a textbook dedicated to the topic and recreates the excitement surrounding the scientific revolution sparked by the discovery of RNA interference in 1998.Students and instructors alike will profit from the author's exclusive first-hand knowledge, drawing on his breakthrough discoveries at the Tuschl lab at Rockefeller University. Gunter Meister abandons the traditionalist treatment of nucleic acids found in most biochemistry and molecular biology texts, adopting instead a modern approach in both concept and scope.The text is divided into three parts, on mRNA, non-coding RNA, and RNomics, and the author addresses the traditional roles of RNA in the transmission and regulation of genetic information, as well as the recently discovered functions of small RNA species in pathogen defense, cell differentiation and higher-level genomic regulation. All set to become the standard for teaching molecular science to biologists and biochemists.

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  • Molecular Biology of RNA
    Molecular Biology of RNA

    RNA plays a central, and until recently, somewhat underestimated role in the genetics underlying all forms of life on earth.This versatile molecule not only plays a crucial part in the synthesis of proteins from a DNA template, but is also intrinsically involved in the regulation of gene expression, and can even act as a catalyst in the form of a ribozyme.This latter property has led to the hypothesis that RNA - rather than DNA - could have played an essential part in the origin of life itself. This landmark text provides a systematic overview of the exciting and rapidly moving field of RNA biology.Key pioneering experiments, which provided the underlying evidence for what we now know, are described throughout, while the relevance of the subject to human disease is highlighted via frequent boxes. For the second edition of Molecular Biology of RNA, more introductory material has been incorporated at the beginning of the text, to aid students studying the subject for the first time.Throughout the text, new material has been included - particularly in relation to RNA binding domains, non-coding RNAs, and the connection between RNA biology and epigenetics.Finally, a new closing chapter discusses how exciting new technologies are being used to explore current topical areas of research.

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  • Is learning programming and software development very challenging?

    Learning programming and software development can be challenging for some people, as it requires logical thinking, problem-solving skills, and attention to detail. However, with dedication, practice, and the right resources, it is definitely achievable. Breaking down complex concepts into smaller, more manageable parts and seeking help from online tutorials, courses, and communities can make the learning process easier and more enjoyable. Ultimately, the level of challenge will vary depending on the individual's background, experience, and learning style.

  • What is RNA self-replication?

    RNA self-replication is a process where RNA molecules are able to catalyze their own replication without the need for external enzymes. This ability is crucial for the early evolution of life on Earth, as it is believed to be a key step in the transition from prebiotic chemistry to the emergence of life. RNA self-replication involves the RNA molecule acting as both a template and an enzyme, allowing it to make copies of itself. This process is a fundamental aspect of the RNA world hypothesis, which suggests that RNA played a central role in the origin of life.

  • What are DNA and RNA?

    DNA (deoxyribonucleic acid) and RNA (ribonucleic acid) are both types of nucleic acids that are essential for the storage and expression of genetic information in living organisms. DNA is the molecule that carries the genetic instructions for the development, functioning, growth, and reproduction of all known living organisms and many viruses. It is a double-stranded molecule that is composed of a long chain of nucleotides. RNA, on the other hand, is a single-stranded molecule that is involved in various biological roles, including coding, decoding, regulation, and expression of genes. It plays a crucial role in the synthesis of proteins from the genetic information encoded in DNA.

  • What happens first during RNA processing?

    During RNA processing, the initial step is the removal of introns from the pre-mRNA molecule through a process called splicing. This results in the formation of a mature mRNA molecule that only contains exons. Following splicing, a 5' cap is added to the beginning of the mRNA molecule, which helps protect it from degradation and aids in the initiation of translation. Finally, a poly-A tail is added to the 3' end of the mRNA molecule, which also plays a role in stabilizing the mRNA and facilitating its export from the nucleus.

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  • Programming Machine Learning : From Coding to Deep Learning
    Programming Machine Learning : From Coding to Deep Learning

    You've decided to tackle machine learning - because you're job hunting, embarking on a new project, or just think self-driving cars are cool.But where to start? It's easy to be intimidated, even as a software developer.The good news is that it doesn't have to be that hard.Master machine learning by writing code one line at a time, from simple learning programs all the way to a true deep learning system.Tackle the hard topics by breaking them down so they're easier to understand, and build your confidence by getting your hands dirty.Peel away the obscurities of machine learning, starting from scratch and going all the way to deep learning.Machine learning can be intimidating, with its reliance on math and algorithms that most programmers don't encounter in their regular work.Take a hands-on approach, writing the Python code yourself, without any libraries to obscure what's really going on.Iterate on your design, and add layers of complexity as you go.Build an image recognition application from scratch with supervised learning.Predict the future with linear regression. Dive into gradient descent, a fundamental algorithm that drives most of machine learning.Create perceptrons to classify data. Build neural networks to tackle more complex and sophisticated data sets.Train and refine those networks with backpropagation and batching.Layer the neural networks, eliminate overfitting, and add convolution to transform your neural network into a true deep learning system.Start from the beginning and code your way to machine learning mastery.What You Need: The examples in this book are written in Python, but don't worry if you don't know this language: you'll pick up all the Python you need very quickly.Apart from that, you'll only need your computer, and your code-adept brain.

    Price: 38.50 £ | Shipping*: 0.00 £
  • Maison Rna Spacieuse 5 Chambres
    Maison Rna Spacieuse 5 Chambres


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  • Giant Microbes Giant Microbes Plush (RNA)
    Giant Microbes Giant Microbes Plush (RNA)

    RNA and its molecular cousin DNA are nucleic acids that carry the genetic code. RNA, or ribonucleic acid, acts as an intermediate messenger for genes, the unit of inheritance carried in DNA. Great gift for adults, students, teachers, healthcare professionals, science lovers, gene enthusiasts and everyone interested in who they are and where they are from. Adorable and memorable product provides a hands-on way to learn about health, biology, genes and the amazing field of genetics and heredity Bring RNA and genetics to life with our unique representation of the real RNA structure! Cuddly and soft, this RNA comes with an information card with fascinating facts about RNA and the science of genetics

    Price: 38.59 € | Shipping*: 0.0 €
  • Delphi Gn10324-12B1 12 V Ignition Coil Replaces 30520-Rna-A01 3O52O-Rna-Ao1
    Delphi Gn10324-12B1 12 V Ignition Coil Replaces 30520-Rna-A01 3O52O-Rna-Ao1

    Delphi GN10324-12B1 12 V Ignition Coil Replaces 30520-RNA-A01 3O52O-RNA-AO1Delphi Ignition Coils supply the required electrical energy needed to ignite air-fuel mixtures in an engine’s combustion chamber. They are designed to meet a wide variety of continually evolving requirements for combustion calibrations. Delphi Ignition Coils are also designed to operate dependably and reliably under all operating conditions and throughout the entire engine speed range to help manufacturers meet the highest engine performance, exhaust emissions, and fuel economy objectives. Improved dwell accuracy decreases module and coil temperatures for greater reliability Noise abatement material between laminations reduces audible coil noise Early and precise electronic spark timing helps improve fuel economy and provides faster crank-to-run Lower primary inductance provides high-speed performance Coil per cylinder ramp and fire electronics decrease power dissipation and increase efficiency If you are unsure as to whether this is the correct part for your vehicle, please don't hesitate to contact us. Alternatively please use the cross reference table above. Disclaimer: We have taken every care is taken in putting together lists of suitable vehicle compatibilities and component cross references, they are given for general guidance only, and they do not constitute any contractual term, representation or warranty and as such the supplier (Diy Car Service Parts) do not accept any responsibility in respect of any claim whatsoever and howsoever caused arising from the publication of this listing. It remains the responsibility of you (the customer) to check the specification of this item and carefully compare to your original before ordering/installing.

    Price: 45.83 € | Shipping*: 0.00 €
  • Is mRNA the same as RNA?

    mRNA (messenger RNA) is a type of RNA (ribonucleic acid). RNA is a broad category that includes several types of molecules involved in various cellular processes, including mRNA, tRNA (transfer RNA), and rRNA (ribosomal RNA). mRNA specifically carries the genetic information from the DNA in the cell's nucleus to the ribosomes, where it is used as a template for protein synthesis. Therefore, while mRNA is a type of RNA, not all RNA molecules are mRNA.

  • How can one explain RNA interference simply?

    RNA interference is a natural process in cells that helps regulate gene expression. It involves small RNA molecules, called siRNAs or miRNAs, binding to specific messenger RNA molecules and targeting them for degradation or blocking their translation into proteins. This process can effectively silence the expression of specific genes, allowing cells to control which proteins are produced. In simple terms, RNA interference can be thought of as a way for cells to turn down the volume on certain genes, reducing their impact on cellular processes.

  • How can RNA interference be explained simply?

    RNA interference is a natural process in cells that helps regulate gene expression. It involves small RNA molecules, such as siRNA or miRNA, binding to specific messenger RNA molecules and targeting them for degradation. This process helps control the amount of protein produced by a gene, ultimately influencing various cellular functions. In simple terms, RNA interference can be thought of as a way for cells to "silence" certain genes by using small RNA molecules to block their expression.

  • Do mutated retrogene also arise from xeno-RNA?

    No, mutated retrogene do not arise from xeno-RNA. Mutated retrogene are formed when a processed mRNA transcript is reverse transcribed and integrated back into the genome, leading to a new gene copy. Xeno-RNA, on the other hand, refers to foreign RNA that is introduced into an organism, typically through viral infections or horizontal gene transfer. The two processes are distinct and do not directly lead to the formation of mutated retrogene.

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